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Al-Azhar Journal of Pharmaceutical Sciences
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El-Kelany, A. (2020). PHYTOCHEMICAL AND BIOLOGICAL STUDIES ON SOME MEDICINAL PLANTS. Al-Azhar Journal of Pharmaceutical Sciences, 62(2), 110-134. doi: 10.21608/ajps.2020.118379
Amina El-Kelany. "PHYTOCHEMICAL AND BIOLOGICAL STUDIES ON SOME MEDICINAL PLANTS". Al-Azhar Journal of Pharmaceutical Sciences, 62, 2, 2020, 110-134. doi: 10.21608/ajps.2020.118379
El-Kelany, A. (2020). 'PHYTOCHEMICAL AND BIOLOGICAL STUDIES ON SOME MEDICINAL PLANTS', Al-Azhar Journal of Pharmaceutical Sciences, 62(2), pp. 110-134. doi: 10.21608/ajps.2020.118379
El-Kelany, A. PHYTOCHEMICAL AND BIOLOGICAL STUDIES ON SOME MEDICINAL PLANTS. Al-Azhar Journal of Pharmaceutical Sciences, 2020; 62(2): 110-134. doi: 10.21608/ajps.2020.118379

PHYTOCHEMICAL AND BIOLOGICAL STUDIES ON SOME MEDICINAL PLANTS

Article 8, Volume 62, Issue 2, September and October 2020, Page 110-134  XML PDF (1.48 MB)
Document Type: Original Article
DOI: 10.21608/ajps.2020.118379
Author
Amina El-Kelany
Department of Botany and Microbiology, Faculty of Science, Al-Azhar, University, Girl Branch, Cairo, Egypt.
Abstract
Biological studies on thirteen ethanolic plant extracts (Rosmarinus officinalis ,Ocimum basilicum , Moringa oleifera, Zingiber officinale, Curcuma longa, Nigella sativa ,Cinnamomum verum ,Salvia officinalis, Lepidium sativum, Foeniculum vulgare, Anethum graveolens, Ficus benghalensis and Cinnamomum camphora )revealed that four of them (Rosmarinus officinalis , Zingiber officinale, Cinnamomum verum and Cinnamomum camphora) were the best active against two  bacterial species ;  E. coli , S .aureus  and  one fungus species  C. albicans. Also, their synergistic effects against E. coli, S. aureus  and  C. albicans were studied .So, the phytochemical studies were completed on these four  plants . This study aimed to evaluate the chemical composition of the best active plant extracts. The chemical   major content of   Rosmarinus officinalis  was eucalyptol  (7.48%)   , Zingiber officinale was gingerol (12.73%) , Cinnamomum verum  was      (E)-  cinnamaldehyde (25.55  %  )  and Cinnamomum camphora was eugenol  ( 27 .35% ) . The minimum inhibitory concentration (MIC) values varied from 0.625 to 2.5 mg/ml, for the S. aureus (gram positive bacteria) affected by Rosmarinus officinali,  Zingiber officinale, Cinnamomum verum and Cinnamomum camphora. Respectively. C. albicans was the most effective microorganism by Cinnamomum verum and the least effective microorganism by Rosmarinus officinalis and Cinnamomum camphora. ethanolic extracts, as MIC ranged from 0.15 to 1.25 mg/ml.
Keywords
Escherichia coli; Staphylococcus aureus; Candida albicans; Rosmarinus officinalis; Zingiber officinale; Cinnamomum verum; Cinnamomum camphora; antimicrobial activity; Minimum inhibitory concentration (MIC)
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