In this study, novel 3-substituted 1,2,4-triazino[6,1-b]quinazolines 4a-e, 8-substituted-1H-[1,2,4]triazino[6,1-b]quinazoline-2,4,10(3H)-triones 8a&b and 2-substituted 1,2,4-triazino[6,1-b]quinazolines 9a-d, 10 & 11 were synthesized from 3-amino-6-bromo-2-ethoxycarbonylquinazolin-4(3H)-one (2b) and3-amino-2-aminocarbonylquinazolin-4(3H)-one 7a&b. Some of the newly synthesized compounds were tested for their antimicrobial activity and analgesic activity.
Depending on the obtained results, the newly synthesized compounds possess significant analgesic activity and mild antimicrobial activity.
El-Enany, M. (2015). SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME NEW 1,2,4-TRIAZINO[6,1-B]QUINAZOLINE DERIVATIVES.. Al-Azhar Journal of Pharmaceutical Sciences, 51(1), 164-175. doi: 10.21608/ajps.2015.12504
MLA
Mervat El-Enany. "SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME NEW 1,2,4-TRIAZINO[6,1-B]QUINAZOLINE DERIVATIVES.", Al-Azhar Journal of Pharmaceutical Sciences, 51, 1, 2015, 164-175. doi: 10.21608/ajps.2015.12504
HARVARD
El-Enany, M. (2015). 'SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME NEW 1,2,4-TRIAZINO[6,1-B]QUINAZOLINE DERIVATIVES.', Al-Azhar Journal of Pharmaceutical Sciences, 51(1), pp. 164-175. doi: 10.21608/ajps.2015.12504
VANCOUVER
El-Enany, M. SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME NEW 1,2,4-TRIAZINO[6,1-B]QUINAZOLINE DERIVATIVES.. Al-Azhar Journal of Pharmaceutical Sciences, 2015; 51(1): 164-175. doi: 10.21608/ajps.2015.12504
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