Phytochemical investigation of Antidesma bunius (L.) sprengleaf ethyl acetate extract led to the isolation and identification of amentoflavone 7-O-β-D-glucoside, kaempferol 3-O-β-D-glucoside (Astragalin) and quercetin 7-O-α-L-rhamnopyranosyl-(1′′′→6′′ )-O-β-D-glucopyranoside (Quercetin-7-O-rutinoside) isolated for the first time from A. bunius leaf together with amentoflavone which is previously reported in A.bunius leaf. Detailed phenolics profile in A. bunius leaves ethyl acetate extract using HPLC-DAD-ESI- MS / MS analysis revealed a total of 12 metabolites belonging to flavonoids and phenolic acids. Xanthine oxidase inhibition and hypouricemic effect in vitro bioassays recommends for the potential use of A. bunius leaf extract for the treatment of gout.
Elnaggar, D. (2022). HYPOURICEMIC EFFECT OF ANTIDESMA BUNIUS (L.) LEAVES EXTRACT AND IDENTIFICATION OF FLAVONOID CONTENT. Al-Azhar Journal of Pharmaceutical Sciences, 65(1), 1-15. doi: 10.21608/ajps.2022.223765
MLA
Dina Elnaggar. "HYPOURICEMIC EFFECT OF ANTIDESMA BUNIUS (L.) LEAVES EXTRACT AND IDENTIFICATION OF FLAVONOID CONTENT", Al-Azhar Journal of Pharmaceutical Sciences, 65, 1, 2022, 1-15. doi: 10.21608/ajps.2022.223765
HARVARD
Elnaggar, D. (2022). 'HYPOURICEMIC EFFECT OF ANTIDESMA BUNIUS (L.) LEAVES EXTRACT AND IDENTIFICATION OF FLAVONOID CONTENT', Al-Azhar Journal of Pharmaceutical Sciences, 65(1), pp. 1-15. doi: 10.21608/ajps.2022.223765
VANCOUVER
Elnaggar, D. HYPOURICEMIC EFFECT OF ANTIDESMA BUNIUS (L.) LEAVES EXTRACT AND IDENTIFICATION OF FLAVONOID CONTENT. Al-Azhar Journal of Pharmaceutical Sciences, 2022; 65(1): 1-15. doi: 10.21608/ajps.2022.223765
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