In this study, a total of four endophytic fungi have been isolated from Nigella sativa (Ranunculaceae) seeds growing in Egypt. The isolated fungi were identified morphologically and microscopically up to species to be; Alternaria pluriseptata, Aspergillus tubingensis, Aspergillus parasiticus and Eurotium pseudoglaucus. The extracts of the all identified fungi were screened biologically for antileukemic, cytotoxic, antimalarial, antileishmanial, antimicrobial, antioxidant and anti-inflammatory activities as well as for cannabinoid and opioid receptor binding affinities. All the examined fungal extracts showed good antileukemic activities with Ic50 values ranging from 0.025 to 0.8 µg/ml, while two of them showed cytotoxic activities against Pig kidney epithelial (LLC-PK1) cells. Two fungal extracts exhibited antimalarial activities, three showed antioxidant activities and two exhibited anti-inflammatory activities
Metwaly, A. (2019). COMPARATIVE BIOLOGICAL EVALUATION OF FOUR ENDOPHYTIC FUNGI ISOLATED FROM NIGELLA SATIVA SEEDS. Al-Azhar Journal of Pharmaceutical Sciences, 59(1), 123-136. doi: 10.21608/ajps.2019.64111
MLA
Ahmed Metwaly. "COMPARATIVE BIOLOGICAL EVALUATION OF FOUR ENDOPHYTIC FUNGI ISOLATED FROM NIGELLA SATIVA SEEDS". Al-Azhar Journal of Pharmaceutical Sciences, 59, 1, 2019, 123-136. doi: 10.21608/ajps.2019.64111
HARVARD
Metwaly, A. (2019). 'COMPARATIVE BIOLOGICAL EVALUATION OF FOUR ENDOPHYTIC FUNGI ISOLATED FROM NIGELLA SATIVA SEEDS', Al-Azhar Journal of Pharmaceutical Sciences, 59(1), pp. 123-136. doi: 10.21608/ajps.2019.64111
VANCOUVER
Metwaly, A. COMPARATIVE BIOLOGICAL EVALUATION OF FOUR ENDOPHYTIC FUNGI ISOLATED FROM NIGELLA SATIVA SEEDS. Al-Azhar Journal of Pharmaceutical Sciences, 2019; 59(1): 123-136. doi: 10.21608/ajps.2019.64111
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