SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW N-ETHYL-N-METHYL BENZENE SULFONAMIDE DERIVATIVES

Document Type : Original Article

Author

Organic Chemistry Department, faculty of Pharmacy (Boy’s) Al-Azhar University, Nasr City, Cairo, Egypt.

Abstract

This article describes the synthesis of some novel sulfonamide having the biologically active hydrazones 1,3,4-thiadiazoles and 4-oxothiazolidines  moieties 2-4, 7 and      10-13 respectively.  Starting with 4-acetyl-N-ethyl-N-methyl benzene sulfonamide (1). The structure of the newly synthesized compounds was confirmed by elemental analysis, IR, 1H-NMR and mass spectral data.

Keywords