PHYTOCONSTITUENTS FROM CALLIANDRA HEMATOCEPHALA LEAVES AND THEIR BIOLOGICAL ACTIVITIES

Document Type : Original Article

Author

Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt

Abstract

Phytochemical investigation of Calliandra hematocephala (L` Her) Benth leaves (Leguminosae) resulted in isolation of β-sitosterol (1), Lupeol (2) and dodecanoic acid (3). The compounds were identified by chromatographic (TLC, PC) and spectroscopic analysis (1H NMR and 13C NMR). This is the first report for isolation of compounds 2 and 3 from Calliandra hematocephala. All compounds (1-3) showed antifungal activity against Aspergillus fumigates, Penicillium  italium and Geotricum candidum .They also showed antimicrobial activity against Staphylococcus aureus, Bacillis subtilis and Escherichia coli.