SYNTHESIS OF NEW [1,5]-BENZODIAZEPINE DERIVATIVES CATALYZED BY VARIOUS ALIPHATIC ACIDS

Document Type : Original Article

Author

Organic chemistry department, Al-Azher University, Naser city, Cairo, 11884, Egypt

Abstract

A series of some new[1,5]benzodiazepines has been synthesized using condensation reaction of o-phenelendiamine  with different newly synthesized quinolinyl ketones and effect of different aliphatic acids used as a catalyst was studied. Among the catalytic screened aliphatic acid, chloroacetic acid are a versatile catalyst that modify the yield (60-95%) in short reaction time. 

Keywords