ONE-POT SYNTHESIS AND ANTIMICROBIAL SCREENING OF NEW [1,5] –BENZODIAZEPINE DERIVATIVES CATALYZED BY TBAB

Document Type : Original Article

Author

Organic Chemistry Department, Al-Azher University, Nasr City , Cairo,11884, Egypt

Abstract

A new [1,5]-benzodiazepines (VI) were synthesized by the reaction of o-phenylenediamine with 2-chloro-3-acetylquinoline in the presence of tetrabutyl ammonium bromide (TBAB) in short reaction time with excellent yield.

Keywords